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CD123, APC, clone: 5B11, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1231-81

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15330670

  • £80.99 / 50µg


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For Research Use Only.


Description

Description

Description: The 5B11 monoclonal antibody reacts with mouse CD123, the alpha chain of the IL-3 receptor. This 60-70kDa transmembrane protein binds to IL-3 with low affinity by itself and when associated with either CD131 (common beta chain) or AIC2A (IL-3beta) binds IL-3 with high affinity. CD123 does not transduce any intracellular signals upon binding IL-3 and requires the beta chain for this function.Applications Reported: This 5B11 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 5B11 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD123
5B11
APC
Conjugated
Rat
50μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
'Interleukin-3 Receptor alpha, IL-3Ra
IgG2a
RUO
Primary
Murine
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