missing translation for 'onlineSavingsMsg'
Learn More

CD123 Mouse anti-Human, PerCP-Cyanine5.5, Clone: 6H6, eBioscience™

Mouse Monoclonal Antibody

£94.00 - £225.00

Specifications

Antigen CD123
Clone 6H6
Target Species Human
Conjugate PerCP-Cyanine5.5
Isotype IgG1, kappa
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15559026
View Documents
Affymetrix eBioscience
45-1239-41
25 Tests
£94.00
25 tests
View alternative products
Save Up to 
»
Estimated Shipment: 26-07-2021
Please to purchase this item. Need a web account? Register with us today!
15569026
View Documents
Affymetrix eBioscience
45-1239-42
100 Tests
£225.00
100 tests
View alternative products
Save Up to 
»
In stock, ready to ship: 1
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The 6H6 monoclonal antibody reacts with human CD123, the alpha chain of the IL-3 receptor. This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (common beta chain) binds IL-3 with high affinity. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes. Applications Reported: This 6H6 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 6H6 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
Specifications

Specifications

CD123
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
6H6
PerCP-Cyanine5.5
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO
SDS
Product Certifications

For Research Use Only.