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CD122, clone: TM-b1 (TM-beta1), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1222-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15227197

  • £74.60 / 100µg


Estimated Shipment
01-03-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The TM-b1 monoclonal antibody reacts with mouse CD122, the 90-110kDa interleukin-2 receptor beta chain (IL-2R beta). CD122 is expressed by NK cells and some T cells in the periphery, and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. High affinity binding of IL-2 to the IL-2 receptor is inhibited by the TM-b1 antibody.Applications Reported: The TM-b1 antibody has been reported for use in flow cytometric analysis, cytokine neutralization, and immunoprecipitation.Applications Tested: The TM-beta1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD122
TM-b1 (TM-beta1)
Unconjugated
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Immunoprecipitation
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-2 Receptor beta, IL-2Rb
IgG2b
RUO
Primary
Murine
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