CD120b (TNF Receptor II) Armenian Hamster anti-Mouse, Clone: TR75-54, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1203-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15267187

Quantity Price
1 £ 152.25 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Antigen CD120b (TNF Receptor II)
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Enzyme Linked Immunosorbent Assay
Applications Flow Cytometry
Applications Functional Assay
Applications Immunoprecipitation
Applications Western Blotting
Primary or Secondary Primary
Host Species Armenian Hamster
Isotype IgG
Species Reactivity Mouse
Concentration 0.5mg/mL
Conjugate Unlabeled
Quantity 500μg
Format Purified
Regulatory Status RUO
Gene Alias TNFR2p80, TNF RII, TNFRII
Clone TR75-54

The TR75-54 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor II (TNFRII, TNFR-p80, TNFRSF1B, CD120b). TNFRII is expressed in a variety of cell types and strongly expressed on stimulated T and B lymphocytes. TNFRII is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. The soluble TNF receptors are truncated forms of cell surface receptors with neutralizing activity on both TNF-α and TNF-β. It has been suggested that the proinflammatory and immunosuppressive properties of TNF segregate at the level of its receptors and that the pool of TNF bound to soluble receptors could represent a reservoir to control the TNF release.