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CD11c Mouse anti-Human, eFluor 570, Clone: 118/A5, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 41-9761-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15518966

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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody 118/A5 recognizes human CD11c, a 150 kD type I transmembrane protein which is also known as integrin alpha X. Integrins are heterodimeric integral membrane proteins made up of an alpha and a beta chain and are involved in cell adhesion. The CD11/CD18 adhesion molecules consist of three heterodimers sharing a common beta subunit (CD18) with a distinct alpha subunit (CD11a, CD11b, CD11c). The CD11c/CD18 complex is expressed on dendritic cells (highly expressed on type 1 myeloid DCs), monocytes, macrophages, granulocytes, NK cells, and subsets of T and B cells. CD11c is also expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. CD11c plays a role in adhesion and CTL killing through its interactions with CD54, iC3b and fibrinogen.
Specifications

Specifications

CD11c
118/A5
eFluor 570
Conjugated
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Microscopy
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Integrin alpha X
IgG2b
RUO
Primary
Human