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CD11c, eFluor 450, clone: N418, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-0114-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15361690

  • £140.77 / 100µg


EU Stock 8
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Disclaimers:

For Research Use Only.


Description

Description

Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.Applications Reported: This N418 antibody has been reported for use in flow cytometric analysis.Applications Tested: This N418 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD11c
N418
eFluor 450
Conjugated
Armenian Hamster
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha
IgG
RUO
Primary
Murine
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