CD11c Armenian Hamster anti-Mouse, Clone: N418, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0114-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15246807

Quantity Price
1 £ 66.65 / 100µg
EU Stock 1
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Gene Alias Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha
Conjugate Unlabeled
Regulatory Status RUO
Primary or Secondary Primary
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Isotype IgG
Clone N418
Antigen CD11c
Species Reactivity Mouse
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL
Quantity 100μg
Host Species Armenian Hamster
Storage Requirements Store at 2-8°C.

The N418 monoclonal antibody reacts with mouse CD11c, the integrin αX. CD11c non-covalently associates with β2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.