CD11c Armenian Hamster anti-Mouse, Clone: N418, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0114-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15256807

Quantity Price
1 £ 140.02 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Gene Alias Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone N418
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Regulatory Status RUO
Concentration 0.5mg/mL
Isotype IgG
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Antigen CD11c
Format Purified
Host Species Armenian Hamster
Quantity 500μg

The N418 monoclonal antibody reacts with mouse CD11c, the integrin αX. CD11c non-covalently associates with β2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.