CD11b Rat anti-Mouse, Clone: M1/70, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0112-85

500UG:ANTI-MOUSE CD11B FUNCTIONAL GRADE PURIFIED

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15258377

Quantity Price
1 £ 194.0 / 500µg
Estimated Shipment date
from Supplier 27-02-2017
Add to basket


Description and Specification

Specification

Antigen CD11b
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias Integrin alpha M, ITGAM, Mac-1 alpha (Mac1A), Complement Receptor 3 alpha (CR3A)
Host Species Rat
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Isotype IgG2b
Regulatory Status RUO
Species Reactivity Mouse
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone M1/70
Conjugate Unlabeled
Quantity 500μg
Storage Requirements Store at 2-8°C.

The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170kDa integrin αM. CD11b non-covalently associates with CD18 to form αMβ2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.