CD11b Rat anti-Mouse, Alexa Fluor 488, Clone: M1/70, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-0112-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15361980

Quantity Price
1 £ 61.11 / 25µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Gene Alias Integrin alpha M, ITGAM, Mac-1 alpha (Mac1A), Complement Receptor 3 alpha (CR3A)
Isotype IgG2b
Host Species Rat
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Antigen CD11b
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Conjugate Alexa Fluor 488
Primary or Secondary Primary
Quantity 25μg
Clone M1/70
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated

The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170kDa integrin αM. CD11b non-covalently associates with CD18 to form αMβ2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.