CD11b/c Mouse anti-Rat, PerCP-eFluor 710, Clone: OX42, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-0110-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15351230

Quantity Price
1 £ 157.56 / 100µg
EU Stock 7
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Description and Specification

Specification

Host Species Murine
Format Conjugated
Gene Alias C3bi, Mac-1, Integrin alpha M, CR4
Regulatory Status RUO
Applications Flow Cytometry
Antigen CD11b/c
Species Reactivity Rat
Primary or Secondary Primary
Isotype IgG2a
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone OX42
Monoclonal or Polyclonal Monoclonal
Conjugate PerCP-eFluor 710
Concentration 0.2mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

This OX42 monoclonal antibody reacts with rat CD11b and CD11c. CD11b, also known as integrin alpha M or Mac-1, is a component of complement receptor 3 (CR3). CD11c, also known as integrin alpha X, is a component of complement receptor 4 (CR4). CD11b and CD11c are expressed on immune cells such as macrophages, monocytes, granulocytes, and dendritic cells. OX42 has also been shown to detect microglia in the brain, as well as cells of the liver and epidermis.

The OX42 antibody has been reported to inhibit complement-mediated rosette formation by granulocytes and macrophages. Moreover, studies demonstrate that OX42 can inhibit granulocyte aggregation.