CD11b/c Mouse anti-Rat, PerCP-eFluor 710, Clone: OX42, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-0110-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15351230

Quantity Price
1 £ 157.56 / 100µg
EU Stock 8
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Description and Specification

Specification

Format Conjugated
Antigen CD11b/c
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias C3bi, Mac-1, Integrin alpha M, CR4
Host Species Mouse
Applications Flow Cytometry
Isotype IgG2a
Quantity 100μg
Regulatory Status RUO
Species Reactivity Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone OX42
Concentration 0.2mg/mL
Conjugate PerCP-eFluor 710

This OX42 monoclonal antibody reacts with rat CD11b and CD11c. CD11b, also known as integrin alpha M or Mac-1, is a component of complement receptor 3 (CR3). CD11c, also known as integrin alpha X, is a component of complement receptor 4 (CR4). CD11b and CD11c are expressed on immune cells such as macrophages, monocytes, granulocytes, and dendritic cells. OX42 has also been shown to detect microglia in the brain, as well as cells of the liver and epidermis.

The OX42 antibody has been reported to inhibit complement-mediated rosette formation by granulocytes and macrophages. Moreover, studies demonstrate that OX42 can inhibit granulocyte aggregation.