CD11b/c Mouse anti-Rat, eFluor 660, Clone: OX42, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-0110-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15321850

Quantity Price
1 £ 131.46 / 100µg
EU Stock 3
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Description and Specification

Specification

Species Reactivity Rat
Clone OX42
Antigen CD11b/c
Concentration 0.2mg/mL
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Conjugate eFluor 660
Isotype IgG2a
Quantity 100μg
Gene Alias C3bi, Mac-1, Integrin alpha M, CR4
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Host Species Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO

This OX42 monoclonal antibody reacts with rat CD11b and CD11c. CD11b, also known as integrin alpha M or Mac-1, is a component of complement receptor 3 (CR3). CD11c, also known as integrin alpha X, is a component of complement receptor 4 (CR4). CD11b and CD11c are expressed on immune cells such as macrophages, monocytes, granulocytes, and dendritic cells. OX42 has also been shown to detect microglia in the brain, as well as cells of the liver and epidermis.

The OX42 antibody has been reported to inhibit complement-mediated rosette formation by granulocytes and macrophages. Moreover, studies demonstrate that OX42 can inhibit granulocyte aggregation.