CD117 (c-kit) Rat anti-Mouse, PE-eFluor 610, Clone: 2B8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 61-1171-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15560457

Quantity Price
1 £ 48.89 / 25µg
Estimated Shipment date
from Supplier 05-04-2017
Add to basket


Description and Specification

Specification

Concentration 0.2mg/mL
Isotype IgG2b
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse, Pig
Format Conjugated
Gene Alias Steel Factor Receptor
Applications Flow Cytometry
Clone 2B8
Antigen CD117 (c-kit)
Regulatory Status RUO
Quantity 25μg
Conjugate PE-eFluor 610

The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor, and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1 low) and negative for lineage markers. The interaction of the mouse c-Kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.