CD117 (c-kit) Rat anti-Mouse, PE, Clone: ACK2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1172-83

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15238649

Quantity Price
1 £ 174.09 / 200µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Conjugate PE
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD117 (c-kit)
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Gene Alias SCFR, Steel Factor Receptor
Primary or Secondary Primary
Quantity 200μg
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Isotype IgG2b
Concentration 0.2mg/mL
Clone ACK2
Applications Flow Cytometry
Regulatory Status RUO
Species Reactivity Mouse
Format Conjugated

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.