CD117 (c-kit) Rat anti-Mouse, PE, Clone: 2B8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1171-81

50UG ANTI-MOUSE CD117 (C-KIT) PE

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15298639

Quantity Price
1 £ 82.0 / 50µg
Estimated Shipment date
from Supplier 27-02-2017
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Description and Specification

Specification

Antigen CD117 (c-kit)
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Steel Factor Receptor
Applications Flow Cytometry
Quantity 50μg
Regulatory Status RUO
Species Reactivity Mouse, Pig
Primary or Secondary Primary
Conjugate PE
Host Species Rat
Isotype IgG2b
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Clone 2B8
Concentration 0.2mg/mL

The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor, and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1 low) and negative for lineage markers. The interaction of the mouse c-Kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.