CD117 (c-kit) Rat anti-Mouse, eFluor 450, Clone: 2B8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1171-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15579706

Quantity Price
1 £ 124.0 / 100µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry
Quantity 100μg
Isotype IgG2b
Concentration 0.2mg/mL
Primary or Secondary Primary
Gene Alias Steel Factor Receptor
Host Species Rat
Clone 2B8
Regulatory Status RUO
Format Conjugated
Species Reactivity Mouse, Pig
Antigen CD117 (c-kit)
Conjugate eFluor 450
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor, and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1 low) and negative for lineage markers. The interaction of the mouse c-Kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.