CD117 (c-kit) Rat anti-Mouse, Clone: ACK2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1172-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208547

Call for latest availability
+44 (0)1509 555500
Add to basket


Description and Specification

Specification

Isotype IgG2b
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Quantity 500μg
Gene Alias SCFR, Steel Factor Receptor
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Clone ACK2
Format Purified
Host Species Rat
Concentration 1mg/mL
Primary or Secondary Primary
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Antigen CD117 (c-kit)

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.