CD117 (c-kit) Rat anti-Mouse, Clone: ACK2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1172-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208547

Quantity Price
1 £ 170.59 / 500µg
EU Stock 3
Add to basket


Description and Specification

Specification

Isotype IgG2b
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Quantity 500μg
Gene Alias SCFR, Steel Factor Receptor
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Clone ACK2
Format Purified
Host Species Rat
Concentration 1mg/mL
Primary or Secondary Primary
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Antigen CD117 (c-kit)

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.