CD117 (c-kit) Rat anti-Mouse, Clone: ACK2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1172-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298537

Quantity Price
1 £ 91.11 / 100µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Conjugate Unlabeled
Quantity 100μg
Gene Alias SCFR, Steel Factor Receptor
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Format Purified
Regulatory Status RUO
Antigen CD117 (c-kit)
Isotype IgG2b
Clone ACK2
Species Reactivity Mouse
Formulation aqueous buffer, no sodium azide
Host Species Rat
Concentration 1mg/mL
Storage Requirements Store at 2-8°C.

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.