CD117 (c-kit) Rat anti-Mouse, Clone: ACK2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1172-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15207187

Quantity Price
1 £ 42.19 / 50µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Isotype IgG2b
Concentration 0.5mg/mL
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Conjugate Unlabeled
Primary or Secondary Primary
Clone ACK2
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 50μg
Monoclonal or Polyclonal Monoclonal
Antigen CD117 (c-kit)
Gene Alias SCFR, Steel Factor Receptor
Regulatory Status RUO
Format Purified
Species Reactivity Mouse
Host Species Rat

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.