CD117 (c-kit) Rat anti-Mouse, Clone: 2B8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1171-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15277177

Quantity Price
1 £ 42.19 / 50µg
Estimated Shipment date
from Supplier 08-05-2017
Add to basket


Description and Specification

Specification

Clone 2B8
Host Species Rat
Applications Flow Cytometry
Applications Immunoprecipitation
Primary or Secondary Primary
Conjugate Unlabeled
Gene Alias Steel Factor Receptor
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL
Quantity 50μg
Species Reactivity Mouse, Pig
Monoclonal or Polyclonal Monoclonal
Isotype IgG2b
Storage Requirements Store at 2-8°C.
Regulatory Status RUO
Format Purified
Antigen CD117 (c-kit)

The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor, and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1 low) and negative for lineage markers. The interaction of the mouse c-Kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.