CD117 (c-kit) Rat anti-Mouse, Biotin, Clone: 2B8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-1171-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15239699

Quantity Price
1 £ 158.36 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Isotype IgG2b
Conjugate Biotin
Format Conjugated
Gene Alias Steel Factor Receptor
Clone 2B8
Quantity 500μg
Concentration 0.5mg/mL
Antigen CD117 (c-kit)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Species Reactivity Mouse, Pig
Applications Flow Cytometry

The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor, and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1 low) and negative for lineage markers. The interaction of the mouse c-Kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.