CD117 (c-kit) Rat anti-Mouse, APC-eFluor 780, Clone: ACK2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-1172-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15371640

Quantity Price
1 £ 67.24 / 25µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Isotype IgG2b
Conjugate APC-eFluor 780
Antigen CD117 (c-kit)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Quantity 25μg
Host Species Rat
Clone ACK2
Species Reactivity Mouse
Gene Alias SCFR, Steel Factor Receptor
Primary or Secondary Primary
Applications Flow Cytometry
Concentration 0.2mg/mL

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.