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CD117 (c-kit) Rat anti-Mouse, APC-eFluor 780, Clone: ACK2, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 47-1172-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15381640

  • £124.00 / 100µg


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.
Specifications

Specifications

CD117 (c-kit)
ACK2
APC-eFluor™ 780
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
SCFR, Steel Factor Receptor
IgG2b
RUO
Primary
Murine
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