CD117 (c-kit) Mouse anti-Human, PE, Clone: YB5.B8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1179-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15546866

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Gene Alias cKit, Mast/Stem Cell Growth Factor Receptor
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests
Isotype IgG1
Species Reactivity Human
Clone YB5.B8
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate PE
Antigen CD117 (c-kit)
Format Conjugated
Host Species Mouse
Applications Flow Cytometry
Primary or Secondary Primary
Regulatory Status RUO
Concentration 5μL (0.25μg)/test

The YB5.B8 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.

When interested in staining HSCs from peripheral blood, we recommend the use of clone 104D2. Please refer to cat. 17-1178.