CD117 (c-kit) Mouse anti-Human, APC, Clone: YB5.B8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1179-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15507996

Quantity Price
1 £ 176.7 / 100 tests
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias cKit, Mast/Stem Cell Growth Factor Receptor
Antigen CD117 (c-kit)
Primary or Secondary Primary
Species Reactivity Human
Regulatory Status RUO
Concentration 5μL (0.5μg)/test
Host Species Mouse
Quantity 100 tests
Conjugate APC
Clone YB5.B8
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Applications Flow Cytometry

The YB5.B8 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.

When interested in staining HSCs from peripheral blood, we recommend the use of clone 104D2. Please refer to cat. 17-1178.