CD117 (c-kit) Mouse anti-Human, APC, Clone: YB5.B8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1179-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15597986

Quantity Price
1 £ 84.99 / 25 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Species Reactivity Human
Concentration 5μL (0.5μg)/test
Applications Flow Cytometry
Conjugate APC
Antigen CD117 (c-kit)
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests
Gene Alias cKit, Mast/Stem Cell Growth Factor Receptor
Isotype IgG1
Host Species Mouse
Primary or Secondary Primary
Clone YB5.B8
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The YB5.B8 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.

When interested in staining HSCs from peripheral blood, we recommend the use of clone 104D2. Please refer to cat. 17-1178.