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CD115 (c-fms) Monoclonal Antibody (12-3A3-1B10), Super Bright™ 436, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£129.00 - £300.00
Specifications
Antigen | CD115 (c-fms) |
---|---|
Clone | 12-3A3-1B10 |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15875503
|
Affymetrix eBioscience
62-1159-42 |
100 Tests |
£300.00
Pack of 100 |
Estimated Shipment: 15-04-2024 Log in to see stock. |
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15865503
|
Affymetrix eBioscience
62-1159-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: CD115 or Colony-Stimulating Factor-1 Receptor (CSF-1R) is expressed on cells committed to the monocyte lineage and osteoclasts. CSF-1R is a disulfide-linked homodimer, which upon binding of its ligand, CSF-1, undergoes tyrosine autophosphorylation and subsequently, phosphorylates other membrane-proximal downstream targets which results in cytoskeletal remodeling, gene transcription and protein translation. CSF-1R activation promotes the survival, proliferation and differentiation of mononuclear phagocytes and the spreading and motility of macrophages. In osteoclasts, CSF-1R synergizes with RANKL to regulate the differentiation of mononuclear phagocytes to osteoclasts. Applications Reported: This 12-3A3-1B10 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 12-3A3-1B10 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome.
CD115 (c-fms) Monoclonal antibody specifically detects CD115 (c-fms) in Human samples. It is validated for Flow Cytometry.Specifications
CD115 (c-fms) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
P07333 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
12-3A3-1B10 | |
Flow Cytometry | |
Super Bright 436 | |
Rat | |
Human | |
1436 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |