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CD115 (c-fms) Monoclonal Antibody (12-3A3-1B10), Super Bright™ 436, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£129.00 - £300.00

Specifications

Antigen CD115 (c-fms)
Clone 12-3A3-1B10
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15875503
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Affymetrix eBioscience
62-1159-42
100 Tests
£300.00
Pack of 100
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Estimated Shipment: 15-04-2024
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15865503
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Affymetrix eBioscience
62-1159-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: CD115 or Colony-Stimulating Factor-1 Receptor (CSF-1R) is expressed on cells committed to the monocyte lineage and osteoclasts. CSF-1R is a disulfide-linked homodimer, which upon binding of its ligand, CSF-1, undergoes tyrosine autophosphorylation and subsequently, phosphorylates other membrane-proximal downstream targets which results in cytoskeletal remodeling, gene transcription and protein translation. CSF-1R activation promotes the survival, proliferation and differentiation of mononuclear phagocytes and the spreading and motility of macrophages. In osteoclasts, CSF-1R synergizes with RANKL to regulate the differentiation of mononuclear phagocytes to osteoclasts. Applications Reported: This 12-3A3-1B10 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 12-3A3-1B10 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome.

CD115 (c-fms) Monoclonal antibody specifically detects CD115 (c-fms) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD115 (c-fms)
5 μL/Test
Monoclonal
Liquid
RUO
P07333
IgG2a κ
Affinity chromatography
Antibody
12-3A3-1B10
Flow Cytometry
Super Bright 436
Rat
Human
1436
Primary
4° C, store in dark, DO NOT FREEZE!
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