CD109 Mouse anti-Human, PE, Clone: HU17, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 12-1099-41
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionThe HU17 monoclonal antibody reacts with human CD109, also known as the platelet-specific Gov antigen. CD109, a GPI-anchored monomeric glycoprotein, exists in two isoforms of 120 and 150 kDa, which are proteolytically degraded from a 170kDa form. CD109 is expressed on activated T cells, activated platelets and endothelial cells. CD109 expression is also found on a subset of CD34+ cells in adult and fetal bone marrow which contain megakaryocyte, myeloid, erythroid and multilineage progenitors, as well as pluriopotent hematopoietic stem cells. Recently, it has been demonstrated that CD109 is expressed on a variety of human cancer cell lines, and also lung and esophogeal cell carcinomas. In addition, CD109 was recently found to be a negative regulator of TGF-β in keratinocytes.
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|