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CD109 Mouse anti-Human, PE, Clone: HU17, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1099-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15566856

  • £66.65 / 25 tests


Estimated Shipment date
from Supplier 30-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The HU17 monoclonal antibody reacts with human CD109, also known as the platelet-specific Gov antigen. CD109, a GPI-anchored monomeric glycoprotein, exists in two isoforms of 120 and 150 kDa, which are proteolytically degraded from a 170kDa form. CD109 is expressed on activated T cells, activated platelets and endothelial cells. CD109 expression is also found on a subset of CD34+ cells in adult and fetal bone marrow which contain megakaryocyte, myeloid, erythroid and multilineage progenitors, as well as pluriopotent hematopoietic stem cells. Recently, it has been demonstrated that CD109 is expressed on a variety of human cancer cell lines, and also lung and esophogeal cell carcinomas. In addition, CD109 was recently found to be a negative regulator of TGF-β in keratinocytes.
Description & Specifications

Specifications

CD109
HU17
PE
Conjugated
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal