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CD106 (VCAM-1) Rat anti-Mouse, Clone: 429, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-1061-81

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15248537

  • £48.31 / 50µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
Specifications

Specifications

CD106
429
Unconjugated
Purified
Rat
50μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
VCAM1, vascular cell adhesion molecule-1
IgG2a
RUO
Primary
Murine
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