CD106 (VCAM-1) Rat anti-Mouse, Clone: 429, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1061-82


UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15258537

Quantity Price
1 £126.00 / 100µg
Estimated Shipment date
from Supplier 01-11-2016
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Description and Specification


Antigen CD106 (VCAM-1)
Applications Flow Cytometry
Applications Functional Assay
Clone 429
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias VCAM1, vascular cell adhesion molecule-1
Host Species Rat
Isotype IgG2a
Quantity 100μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.