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CD106 (VCAM-1) Mouse anti-Rat, Clone: eBioMR106 (MR106), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1060-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15247157

  • £91.11 / 100µg


Estimated Shipment
02-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
Description & Specifications

Specifications

CD106 (VCAM-1)
eBioMR106 (MR106)
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
VCAM1, vascular cell adhesion molecule-1
IgG1
RUO
Primary
Rat