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CD106 (VCAM-1) Mouse anti-Rat, Biotin, Clone: eBioMR106 (MR106), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-1060-81

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15209679

  • £60.53 / 50µg


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For Research Use Only.


Description

Description

The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
Specifications

Specifications

CD106
eBioMR106 (MR106)
Biotin
Conjugated
Murine
50μg
Store at 2-8°C. Do not freeze.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
VCAM1, vascular cell adhesion molecule-1
IgG1
RUO
Primary
Rat
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