CD106 (VCAM-1) Mouse anti-Human, PE-Cy7, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-1069-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15558456

Quantity Price
1 £ 182.82 / 100 tests
EU Stock 1
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Description and Specification

Specification

Species Reactivity Human
Antigen CD106 (VCAM-1)
Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Host Species Mouse
Concentration 5μL (0.25μg)/test
Primary or Secondary Primary
Conjugate PE-Cy7
Regulatory Status RUO
Gene Alias vascular cell adhesion molecule-1
Applications Flow Cytometry
Quantity 100 tests
Clone STA
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.