CD106 (VCAM-1) Mouse anti-Human, PE, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1069-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15516856

Quantity Price
1 £ 133.91 / 100 tests
EU Stock 1
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Isotype IgG1
Concentration 5μL (0.125μg)/test
Species Reactivity Human
Quantity 100 tests
Monoclonal or Polyclonal Monoclonal
Antigen CD106 (VCAM-1)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Regulatory Status RUO
Clone STA
Conjugate PE
Applications Flow Cytometry
Gene Alias vascular cell adhesion molecule-1
Primary or Secondary Primary

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.