CD106 (VCAM-1) Mouse anti-Human, PE, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1069-41

25TEST Anti-Human CD106 (VCAM-1) PE

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15506856

Quantity Price
1 £ 92.2 / 25 tests
Estimated Shipment date
from Supplier 08-12-2016
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Description and Specification

Specification

Antigen CD106 (VCAM-1)
Applications Flow Cytometry
Clone STA
Concentration 5μL (0.125μg)/test
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias vascular cell adhesion molecule-1
Host Species Mouse
Isotype IgG1
Quantity 25 tests
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.