CD106 (VCAM-1) Mouse anti-Human, PE, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1069-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15506856

Quantity Price
1 £ 60.53 / 25 tests
EU Stock 4
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Description and Specification

Specification

Primary or Secondary Primary
Concentration 5μL (0.125μg)/test
Gene Alias vascular cell adhesion molecule-1
Isotype IgG1
Quantity 25 tests
Host Species Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Clone STA
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Antigen CD106 (VCAM-1)
Species Reactivity Human
Conjugate PE
Format Conjugated

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.