CD106 (VCAM-1) Mouse anti-Human, FITC, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-1069-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15516476

Quantity Price
1 £ 60.53 / 25 tests
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Gene Alias vascular cell adhesion molecule-1
Antigen CD106 (VCAM-1)
Host Species Mouse
Species Reactivity Human
Clone STA
Isotype IgG1
Format Conjugated
Concentration 5μL (1μg)/test
Conjugate FITC
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Quantity 25 tests

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.