CD106 (VCAM-1) Mouse anti-Human, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1069-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15297157

Quantity Price
1 £ 29.97 / 25µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Gene Alias vascular cell adhesion molecule-1
Storage Requirements Store at 2-8°C.
Format Purified
Host Species Mouse
Clone STA
Conjugate Unlabeled
Concentration 0.5mg/mL
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Regulatory Status RUO
Primary or Secondary Primary
Antigen CD106 (VCAM-1)
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.