CD106 (VCAM-1) Mouse anti-Human, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1069-80

Product Code. 15297157

Disclaimers:

For Research Use Only.

Description

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α₄β₁ (VLA-4, CD49d/CD29) and Integrin α₄β₇ (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.

Specifications

• Antigen: CD106 (VCAM-1)
• Clone: STA
• Conjugate: Unconjugated
• Format: Purified
• Host Species: Murine
• Quantity: 25μg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Immunohistochemistry (Frozen)
• Concentration: 0.5mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Gene Alias: vascular cell adhesion molecule-1
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human