CD106 (VCAM-1) Mouse anti-Human, Biotin, Clone: STA, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-1069-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15269679

Quantity Price
1 £ 109.45 / 100µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Format Conjugated
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Biotin
Species Reactivity Human
Gene Alias vascular cell adhesion molecule-1
Concentration 0.5mg/mL
Regulatory Status RUO
Antigen CD106 (VCAM-1)
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Isotype IgG1
Clone STA
Quantity 100μg
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze.

The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.