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CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£64.50 - £220.00

Specifications

Antigen CD105 (Endoglin)
Clone MJ7/18
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15279669
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Affymetrix eBioscience
13-1051-81
50 μg
£64.50
50µg
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Estimated Shipment: 08-05-2024
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15289669
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Affymetrix eBioscience
13-1051-82
100 μg
£165.00
100µg
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Estimated Shipment: 08-05-2024
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15299669
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Affymetrix eBioscience
13-1051-85
500 μg
£220.00
500µg
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Estimated Shipment: 10-04-2024
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Description

Description

Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis. Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis. Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells and mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Specifications

Specifications

CD105 (Endoglin)
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
ENG
Primary
4° C, store in dark, DO NOT FREEZE!
ENG
MJ7/18
Flow Cytometry
Biotin
Rat
Mouse
Q63961
13805
IgG2a κ
Affinity chromatography
Antibody
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