CD103 (Integrin alpha E) Mouse anti-Human, PerCP-eFluor 710, Clone: Ber-ACT8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-1037-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599166

Quantity Price
1 £ 163.89 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Quantity 100 tests
Host Species Mouse
Concentration 5μL (0.06μg)/test
Species Reactivity Human
Isotype IgG1
Format Conjugated
Antigen CD103 (Integrin alpha E)
Regulatory Status RUO
Primary or Secondary Primary
Gene Alias Integrin alpha-E, ITGAE
Monoclonal or Polyclonal Monoclonal
Clone Ber-ACT8
Conjugate PerCP-eFluor 710
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The Ber-ACT8 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen (E-cadherin) binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium. Cross-blocking studies suggest that B-Ly7 and Ber-ACT8 see different epitopes.