CD103 (Integrin alpha E) Mouse anti-Human, PE-Cy7, Clone: B-Ly7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-1038-41

Product Code. 15588446

Disclaimers:

For Research Use Only.

Description

The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium.

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Specifications

• Antigen: CD103 (Integrin alpha E)
• Clone: B-Ly7
• Conjugate: PE-Cy7
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Murine
• Quantity: 25 Tests
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Concentration: 5μL (0.25μg)/test
• Format: Conjugated
• Gene Alias: ITGAE
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human