CD103 (Integrin alpha E) Mouse anti-Human, PE, Clone: B-Ly7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1038-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15546846

Quantity Price
1 £ 60.53 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests
Concentration 5μL (0.25 μg)/test
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Host Species Mouse
Antigen CD103 (Integrin alpha E)
Species Reactivity Human
Isotype IgG1
Format Conjugated
Gene Alias ITGAE
Applications Flow Cytometry
Conjugate PE
Monoclonal or Polyclonal Monoclonal
Clone B-Ly7

The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium.