CD103 (Integrin alpha E) Mouse anti-Human, Clone: B-Ly7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1038-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15257147

Quantity Price
1 £ 66.65 / 100µg
EU Stock 1
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Description and Specification

Specification

Clone B-Ly7
Conjugate Unlabeled
Isotype IgG1
Regulatory Status RUO
Antigen CD103 (Integrin alpha E)
Quantity 100μg
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Concentration 0.5mg/mL
Format Purified
Gene Alias ITGAE
Species Reactivity Human
Storage Requirements Store at 2-8°C.

The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium.