CD103 (Integrin alpha E) Mouse anti-Human, Clone: B-Ly7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1038-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15247147

Quantity Price
1 £ 36.08 / 25µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Regulatory Status RUO
Primary or Secondary Primary
Host Species Mouse
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Gene Alias ITGAE
Format Purified
Isotype IgG1
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Antigen CD103 (Integrin alpha E)
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone B-Ly7
Quantity 25μg

The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium.