CD102 (ICAM-2), eFluor 450, clone: 3C4 (mIC2/4), eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 48-1021-80
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionDescription: The monoclonal antibody 3C4 (mIC2/4) recognizes mouse CD102, also known as intercellular adhesion molecule-2 (ICAM-2). CD102, a member of the Immunoglobulin superfamily of receptors with 2 extracellular Ig domains, binds LFA (CD11a/CD18) and Mac-1 (CD11b/CD18), thereby mediating cellular interactions to lymphocytes. CD102 plays a role in NK cytotoxicity and migration, and lymphocyte recirculation. Expression of CD102 is found on most lymphocytes, monocytes and platelets. The 3C4 (mIC2/4) antibody blocks interaction of lymphocytes with antigen presenting cells.Applications Reported: This 3C4 (mIC2/4) antibody has been reported for use in flow cytometric analysis.Applications Tested: This 3C4 (mIC2/4) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|RP23-418O11.10-001, CD102, Icam-2, Ly-60, lymphocyte function-associated AG-1 counter-receptor, Intercellular adhesion molecule 2|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.