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CD102 (ICAM-2), Functional Grade, clone: 3C4 (mIC2/4), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-1021-85

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15587776

  • £176.22 / 500µg


Estimated Shipment date
from Supplier 30-05-2018
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Description

Description

Description: The monoclonal antibody 3C4 (mIC2/4) recognizes mouse CD102, also known as intercellular adhesion molecule-2 (ICAM-2). CD102, a member of the Immunoglobulin superfamily of receptors with 2 extracellular Ig domains, binds LFA (CD11a/CD18) and Mac-1 (CD11b/CD18), thereby mediating cellular interactions to lymphocytes. CD102 plays a role in NK cytotoxicity and migration, and lymphocyte recirculation. Expression of CD102 is found on most lymphocytes, monocytes and platelets. The 3C4 (mIC2/4) antibody blocks interaction of lymphocytes with antigen presenting cells.Applications Reported: This 3C4 (mIC2/4) antibody has been reported for use in flow cytometric analysis and functional assays.Applications Tested: This 3C4 (mIC2/4) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

CD102 (ICAM-2)
Monoclonal
1mg/mL
PBS with no preservative; pH 7.2
P35330
RP23-418O11.10-001, CD102, Icam-2, Ly-60, lymphocyte function-associated AG-1 counter-receptor, Intercellular adhesion molecule 2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Functional Assay
3C4 (mIC2/4)
Functional Grade
Icam2
Purified
Icam2
IgG2a, kappa
500μg
Store at 2-8°C.
Primary
15896
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