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CD102 (ICAM-2), clone: CBR-IC2/2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1029-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15207147

  • £68.96 / 100µg


Estimated Shipment
04-07-2018
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Description

Description

Description: The CBRIC2/2 monoclonal antibody reacts with human ICAM-2 (CD102). ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. ICAM-2 is a ligand of integrin CD11a/CD18 (LFA-1), and also has been reported to bind integrin CD11b/CD18 (Mac-1). ICAM-2 is an intercellular adhesion molecule involved in lymphocyte homing to sites of inflammation. The CBRIC2/2 antibody has been reported to have blocking activity.Applications Reported: This CBRIC2/2 antibody has been reported for use in flow cytometric analysis, immunoblotting, immunoprecipitation, immunohistochemical staining, and functional assays.Applications Tested: This CBRIC2/2 antibody has been tested by flow cytometric analysis of human peripheral blood cells. This can be used at less than or equal to 0.125μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. The CBRIC2/2 antibody has also been found useful for immunoblotting of a human peripheral blood cell lysate, recognizing a protein of approximately 55 kD under non-reducing conditions. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD102 (ICAM-2)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P13598
RP23-418O11.10-001, CD102, Icam-2, Ly-60, lymphocyte function-associated AG-1 counter-receptor, Intercellular adhesion molecule 2
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow CytometryþFunctional AssayþImmunohistochemistryþImmunoprecipitationþWestern Blot
CBRIC2/2
Unconjugated
ICAM2
Purified
ICAM2
IgG2a
100μg
Store at 2-8°C.
Primary
3384
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