CD100 (SEMA4D) Rat anti-Mouse, FITC, Clone: BMA12 (BMA-12), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-1001-81

50UG ANTI-MOUSE CD100 (SEMA4D) FITC

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15258159

Quantity Price
1 £ 101.0 / 50µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen CD100 (SEMA4D)
Applications Flow Cytometry
Clone BMA12 (BMA-12)
Concentration 0.5mg/mL
Conjugate FITC
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Semaphorin 4D
Host Species Rat
Isotype IgG2a
Quantity 50μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The BMA12 monoclonal antibody reacts with mouse CD100, also known as Sema4D. Sema4D/CD100 is a 150kDa transmembrane protein expressed constitutively on T cells and is involved in the activation of B cells through its interaction with CD72. Interaction of these two proteins diminishes the negative signaling normally effected by CD72. CD100 is already expressed strongly on resting T cells and somewhat weakly on B cells, but activation upregulates expression on both cell types. Antigen expression has been reported in Spleen, thymus and lymph nodes.