CD100 (SEMA4D) Mouse anti-Human, Clone: eBio133-1C6 (133-1C6), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1009-80

25UG:ANTI-HUMAN CD100 (SEMA4D) PURIFIED 25 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15217137

Quantity Price
1 £ 101.0 / 25µg
Estimated Shipment date
from Supplier 07-12-2016
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Description and Specification

Specification

Antigen CD100 (SEMA4D)
Applications ELISA Capture
Applications Flow Cytometry
Applications Immunoprecipitation
Clone eBio133-1C6 (133-1C6)
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Semaphorin 4D
Host Species Mouse
Isotype IgM
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.