CD10 Monoclonal Antibody (eBioCB-CALLA (CB-CALLA)), Super Bright™ 600, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
15825553	Affymetrix eBioscience 63-0106-42	100 Tests
15815553	Affymetrix eBioscience 63-0106-41	25 Tests

Description

Description: The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes. Applications Reported: This CB-CALLA antibody has been reported for use in flow cytometric analysis. Applications Tested: This CB-CALLA antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

CD10 Monoclonal antibody specifically detects CD10 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: CD10
• Concentration: 5 μL/Test
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Gene Accession No.: P08473
• Isotype: IgG2b κ
• Purification Method: Affinity chromatography
• Product Type: Antibody

• Clone: eBioCB-CALLA (CB-CALLA)
• Applications: Flow Cytometry
• Conjugate: Super Bright 600
• Host Species: Mouse
• Target Species: Human
• Gene ID (Entrez): 4311
• Primary or Secondary: Primary
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!